Don’t Give Up on Us is a 2006 romantic comedy film, made in the Philippines and directed by Joyce Bernal. The film was the fifth appearance of Judy Ann Santos and Piolo Pascual after Esperanza, Kahit Isang Saglit, Bakit ‘Di Totohanin, and Till There Was You, not including two cameos in Pera o Bayong: The Movie and Jologs. 
The Cinema Evaluation Board (CEB) gave Don’t Give Up on Us a B rating,  which made it eligible for a 65% tax rebate on its earnings in the Philippines.
The Movie Television Ratings Classification Board (MTRCB) gave Don’t Give Up on Us a PG-13 rating  which required parental guidance for viewers under thirteen years of age.
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